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Symbol
Name
ID

Gba1
glucosylceramidase beta 1
MGI:95665

Phenotype annotations related to liver/biliary system

Darker colors indicate more annotations

Human Phenotypes	Portal hypertension	Hepatosplenomegaly	Hepatomegaly	Cirrhosis	Hepatic fibrosis	Hepatitis	Cholelithiasis	Biliary tract obstruction
Disease(s) Associated with GBA1	Portal hypertension	Hepatosplenomegaly	Hepatomegaly	Cirrhosis	Hepatic fibrosis	Hepatitis	Cholelithiasis	Biliary tract obstruction
Gaucher's disease
Gaucher's disease perinatal lethal
Gaucher's disease type I
Gaucher's disease type II
Gaucher's disease type III
Gaucher's disease type IIIC

Mouse Phenotypes		abnormal Kupffer cell morphology	increased hepatocyte apoptosis	enlarged liver	increased liver weight	liver inflammation	abnormal liver morphology	pale liver	abnormal liver physiology
Availability	Mouse Genotype	abnormal Kupffer cell morphology	increased hepatocyte apoptosis	enlarged liver	increased liver weight	liver inflammation	abnormal liver morphology	pale liver	abnormal liver physiology
	Gba1^tm1Rlp/Gba1^tm1Rlp
	Gba1^tm2Ggb/Gba1^tm2Ggb
	Gba1^tm3Ggb/Gba1^tm3Ggb
	Gba1^tm4Ggb/Gba1^tm4Ggb
	Gba1^tm2Ggb/Gba1^tm1Nsb
	Gba1^tm3Ggb/Gba1^tm1Nsb
	Gba1^tm4Ggb/Gba1^tm1Nsb
	Gba1^tm1.1Pmis/Gba1^tm1.1Pmis Tg(Mx1-cre)1Cgn/0 (conditional)
	Gba1^tm1.1Pmis/Gba1^tm1.2Pmis Tg(Mx1-cre)1Cgn/0 (conditional)
	Gba1^tm1Clk/Gba1^tm1.1Clk Tg(Tek-cre)12Flv/0 (conditional)
	Gba1^tm1Karl/Gba1^tm1.1Karl Tg(Mx1-cre)1Cgn/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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